How sample size influences research outcomes

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How sample size influences research outcomes

Sample size calculation is part of the early stages of conducting an epidemiological, clinical or laboratory study. In preparing a scientific paper, there are ethical and methodological indications for its use. Two investigations conducted with the same methodology and achieving equivalent results, but different only in terms of sample size, may point the researcher in different directions when...

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How to Calculate Sample Size and Why

WHY Calculating the sample size is essential to reduce the cost of a study and to prove the hypothesis effectively. HOW Referring to pilot studies and previous research studies, we can choose a proper hypothesis and simplify the studies by using a website or Microsoft Excel sheet that contains formulas for calculating sample size in the beginning stage of the study. MORE There are numerous ...

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Sample size: how many is enough?

Sample size is an element of research design that significantly affects the validity and clinical relevance of the findings identified in research studies. Factors that influence sample size include the effect size, or difference expected between groups or time points, the homogeneity of the study participants, the risk of error that investigators consider acceptable and the rate of participant...

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Sample size determinations in original research

Objectives To assess the completeness of reporting of sample size determinations in unpublished research protocols and to develop guidance for research ethics committees and for statisticians advising these committees. Design Review of original research protocols. Study selection Unpublished research protocols for phase IIb, III, and IV randomised clinical trials of investigational medicinal pr...

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ژورنال

عنوان ژورنال: Dental Press Journal of Orthodontics

سال: 2014

ISSN: 2176-9451

DOI: 10.1590/2176-9451.19.4.027-029.ebo